OCCULT METHEMOGLOBINEMIA due to local anesthetic toxicity potentially is fatal. The Food and Drug Administration has documented 319 cases of methemoglobinemia in patients exposed to topical benzocaine, including 3 cases that resulted in death.1 Even when used as directed by the manufacturer, topical anesthetics that include benzocaine cause methemoglobinemia that may go unnoticed and cause
Some cases of methemoglobinemia are inherited, however, most are caused by exposure to a toxic chemical or drug, such as acetaminophen, moth balls, benzocaine, phenazopyridine, and naphthalene. Methemoglobinemia Average Cost
Methemoglobinemia is a rare cause of hypoxia and can be a diagnostic challenge early in the disease course. The incidence of medication-induced methemoglobinemia is more common than congenital-related methemoglobinemia. The most common cause of methemoglobinemia is exposure to household detergents, illicit drugs, or medications with nitrate or
The second most common cause of methemoglobinemia in our study was iatrogenic nitric oxide (seen mostly with mild methemoglobinemia between 3.1 % and 4.9 %); this is also a well-recognized cause of methemoglobinemia in the published literature,, . In the 2024 2024 data, benzocaine and other local anesthetics were infrequent causes of
Drugs and Toxins Known to Induce Methemoglobinemia. There are a lot of drugs that have been shown to induce methemoglobinemia. Some drugs are commonly used, while others not so much. Here s a table that I prepared for you that reviews some of the more common drugs and toxins known to cause methemoglobinemia:
Lidocaine is also a causative drug for methemoglobinemia. However, reports of lidocaine-induced methemoglobinemia are extremely rare compared with those of
Methemoglobinemia causes tissue hypoxia. Animated Mnemonics Methemoglobin: a changed hemoglobin Methemoglobinemia is a disease
Drugs Causing Methemoglobinemia in Children View Book :- Breathing_difficulty dapsone cyanosis
Most drugs, particularly sulfonamides and phenacetin, that produce methemoglobinemia can also cause sulfhemoglobinemia, although this condition is less common than methemoglobinemia. 11 Symptoms tend to be milder than in patients with methemoglobinemia. The diagnosis is confirmed by elevated levels of sulfhemoglobin by either spectrophotometry
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