Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 Treated definitively with iridectomy. Open-angle glaucoma is not a risk factor for angle-closure glaucoma. Patients may wish to be examined to determine whether they are susceptible to angle closure, and have a prophylactic procedure (e.g., iridectomy), if they are susceptible [see Warnings and Precautions (5.7)] . Bupropion-Containing Products Educate patients that bupropion hydrochloride extended-release tablets (SR) contains the same active ingredient (bupropion hydrochloride) found in ZYBAN, which is used as an aid to smoking cessation treatment, and that bupropion hydrochloride extended-release tablets (SR) should not be used in combination with ZYBAN or any other medications that contain bupropion (such as WELLBUTRIN, the immediate-release formulation and WELLBUTRIN XL or FORFIVO XL, the extended-release formulations, and APLENZIN, the extended-release formulation of bupropion hydrobromide). In addition, there are a number of generic bupropion HCl products for the immediate-, sustained-, and extended-release formulations. Potential for Cognitive and Motor Impairment Advise patients that any CNS-active drug like bupropion hydrochloride extended-release tablets (SR) may impair their ability to perform tasks requiring judgment or motor and cognitive skills. Advise patients that until they are reasonably certain that bupropion hydrochloride extended-release tablets (SR) do not adversely affect their performance, they should refrain from driving an automobile or operating complex, hazardous machinery. Bupropion hydrochloride extended-release tablets (SR) may lead to decreased alcohol tolerance. Concomitant Medications Counsel patients to notify their healthcare provider if they are taking or plan to take any prescription or over-the-counter drugs because bupropion hydrochloride extended-release tablets (SR) and other drugs may affect each others’ metabolisms. Pregnancy Advise patients to notify their healthcare provider if they become pregnant or intend to become pregnant during therapy with bupropion hydrochloride extended-release tablets (SR). Advise patients that there is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to bupropion hydrochloride extended-release tablets (SR) during pregnancy [see Use in Specific Populations (8.1)] . Storage Information Instruct patients to store bupropion hydrochloride extended-release tablets (SR) at room temperature, between 68° and 77°F (20° to 25°C) and keep the tablets dry and out of the light. Administration Information Instruct patients to swallow bupropion hydrochloride extended-release tablets (SR) whole so Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 BUPROPION HCL SR. TAB SR 12H. 100 MG. BUPROPION HCL SR. TAB SR 12H. 150 MG NAPROXEN. TABLET. 375 MG. NAPROXEN. TABLET. 500 MG. NARATRIPTAN HCL. TABLET. 2.5 MG. Bupropion hcl sr 100 bupropion hcl tab er 12hr 100 mg (Wellbutrin sr) bupropion hcl tab er 12hr 150 mg (Wellbutrin sr) bupropion hcl tab er 12hr 200 mg Bupropion hcl sr 100 Drugs appearing on the 90-Day Supply Prescription Drug List can be covered for up to a 90-day BUPROPION HCL SR. TAB SR 12H. 100 MG. BUPROPION HCL SR. TAB SR Bupropion hcl sr 100 Trial of the sustained-release formulation of bupropion HCl, nicotine transdermal system (NTS), the combination of sustained-release bupropion plus NTS, and placebo as an aid to smoking cessation suggest a higher incidence of treatment-emergent hypertension in patients treated with the combination of sustained-release bupropion and NTS. In this trial, 6.1% of subjects treated with the combination of sustained-release bupropion and NTS had treatment-emergent hypertension compared with 2.5%, 1.6%, and 3.1% of subjects treated with sustained-release bupropion, NTS, and placebo, respectively. The majority of these subjects had evidence of pre-existing hypertension. Three subjects (1.2%) treated with the combination of sustained-release bupropion and NTS and 1 subject (0.4%) treated with NTS had study medication discontinued due to hypertension compared with none of the subjects treated with sustained-release bupropion or placebo. Monitoring of blood pressure is recommended in patients who receive the combination of bupropion and nicotine replacement. In a clinical trial of bupropion immediate-release in MDD subjects with stable congestive heart failure (N = 36), bupropion was associated with an exacerbation of pre-existing hypertension in 2 subjects, leading to discontinuation of bupropion treatment. There are no controlled trials assessing the safety of bupropion in patients with a recent history of myocardial infarction or unstable cardiac disease. 5.5 Activation of Mania/Hypomania Antidepressant treatment can precipitate a manic, mixed, or hypomanic manic episode. The risk appears to be increased in patients with bipolar disorder or who have risk factors for bipolar disorder. Prior to initiating bupropion hydrochloride extended-release tablets (SR), screen patients for a history of bipolar disorder and the presence of risk factors for bipolar disorder (e.g., family history of bipolar disorder, suicide, or depression). Bupropion hydrochloride extended-release tablets (SR) are not approved for use in treating bipolar depression. 5.6 Psychosis and Other Neuropsychiatric Reactions Depressed patients treated with bupropion hydrochloride extended-release tablets (SR) have had a variety of neuropsychiatric signs and symptoms, including delusions, hallucinations, psychosis, concentration disturbance, paranoia, and confusion. Some of these patients had a diagnosis of bipolar disorder. In some cases, these symptoms abated upon dose reduction and/or withdrawal of treatment. Instruct patients to contact a healthcare professional if such BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 The Benefits of Bupropion HCL SR 100 mg for Weight Loss . Bupropion HCL SR 100 mg is a medication that has been used for various purposes, including the Bupropion hcl sr 100 bupropion hcl (75 mg tablet, 100 mg tablet) bupropion hcl sr (sr 100 bupropion xl (150 mg tablet, 300 mg tablet) mirtazapine (7.5 Bupropion hcl sr 100 (PA required), Budeprion XL Bupropion HCL (ER, SR; PA required for 100 For budeprion/bupropion SR (Wellbutrin SR 100 mg, 150 mg). ❖ Approvable for Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 The Benefits of Bupropion HCL SR 100 mg for Weight Loss . Bupropion HCL SR 100 mg is a medication that has been used for various purposes, including the Bupropion hcl sr 100 Bupropion hydrochloride extended-release tablets (SR) for a condition for which it was not prescribed. Do not give bupropion hydrochloride extended-release tablets (SR) to other people, even if they have the same symptoms you have. They may harm them. If you take a urine drug screening test, bupropion hydrochloride extended-release tablets (SR) may make the test result positive for amphetamines. If you tell the person giving you the drug screening test that you are taking bupropion hydrochloride extended-release tablets (SR), they can do a more specific drug screening test that should not have this problem. This Medication Guide summarizes important information about bupropion hydrochloride extended-release tablets (SR). If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about bupropion hydrochloride extended-release tablets (SR) that is written for healthcare professionals. For more information about bupropion hydrochloride extended-release tablets (SR), call 1- 866-495-1995. What are the ingredients in bupropion hydrochloride extended-release tablets (SR)? Active ingredient: bupropion hydrochloride USP. Inactive ingredients: colloidal silicon dioxide, diluted hydrochloride acid, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium stearyl fumarate, titanium dioxide and is printed with edible black ink. In addition, the 100 mg tablet contains FD&C Red #40, the 150 mg tablet contains FD&C Blue #1 and D&C Yellow #10 Lake and the 200 mg tablet contains D&C Yellow #10 Lake. The brands listed are trademarks of their respective owners and are not trademarks of the Annora Pharma Private Limited. Medication Guide available at http://camberpharma.com/medication-guides Manufactured for: Camber Pharmaceuticals, Inc. Piscataway, NJ 08854 By: Annora Pharma Pvt. Ltd. Sangareddy - 502313, Telangana, India. This Medication Guide has been approved by the U.S. Food and Drug Administration. Revised: 05/2024 PACKAGE LABEL.PRINCIPAL DISPLAY PANEL Bupropion Tablets 100 mg 60s container Label Bupropion Tablets 150 mg 60s container Label Bupropion Tablets 200 mg 60s container Label Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 Sandoz Bupropion SR bupropion HCl. 100 mg. 150 mg. Tablet. SDZ. - For the treatment of depression. . . Wellbutrin SR bupropion Bupropion hcl sr 100 Wellbutrin SR (Bupropion HCl) Wellbutrin SR (Bupropion HCl) - 150mg, 100 Pills Generic Bupropion hcl sr 100 Wellbutrin SR: 100 mg, 150 mg, 200 mg. Generic: 100 15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL. Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 Diluted hydrochloride acid, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium stearyl fumarate, titanium dioxide and is printed with edible black ink. In addition, the 100 mg tablet contains FD&C Red #40, the 150 mg tablet contains FD&C Blue #1 and D&C Yellow #10 Lake and the 200 mg tablet contains D&C Yellow #10 Lake. FDA approved dissolution test specifications differ from USP. 12. Bupropion - Clinical Pharmacology 12.1 Mechanism of Action The exact mechanism of the antidepressant action of bupropion is not known but is presumed to be related to noradrenergic and/or dopaminergic mechanisms. Bupropion is a relatively weak inhibitor of the neuronal reuptake of norepinephrine and dopamine and does not inhibit the reuptake of serotonin. Bupropion does not inhibit monoamine oxidase. 12.3 Pharmacokinetics Bupropion is a racemic mixture. The pharmacological activity and pharmacokinetics of the individual enantiomers have not been studied. The mean elimination half-life (±SD) of bupropion after chronic dosing is 21 (±9) hours, and steady-state plasma concentrations of bupropion are reached within 8 days. Absorption The absolute bioavailability of bupropion hydrochloride extended-release tablets (SR) in humans has not been determined because an intravenous formulation for human use is not available. However, it appears likely that only a small proportion of any orally administered dose reaches the systemic circulation intact. In rat and dog studies, the bioavailability of bupropion ranged from 5% to 20%. In humans, following oral administration of bupropion hydrochloride extended-release tablets (SR), peak plasma concentration (C max) of bupropion is usually achieved within 3 hours. In a trial comparing chronic dosing with bupropion hydrochloride extended-release tablets (SR) 150 mg twice daily to bupropion immediate-release formulation 100 mg 3 times daily, the steady state C maxfor bupropion after bupropion hydrochloride extended-release tablets (SR) administration was approximately 85% of those achieved after bupropion immediate-release formulation administration. Exposure (AUC) to bupropion was equivalent for both formulations. Bioequivalence was also demonstrated for all three major active metabolites (i.e., hydroxybupropion, threohydrobupropion and erythrohydrobupropion) for both C maxand AUC. Thus, at steady state, bupropion hydrochloride extended-release tablets (SR) given twice daily, and the immediate-release formulation of bupropion given BUPROPION HCL SR. TAB SR 12H. 100 MG. BUPROPION HCL SR. TAB SR 12H. 150 MG NAPROXEN. TABLET. 375 MG. NAPROXEN. TABLET. 500 MG. NARATRIPTAN HCL. TABLET. 2.5 MG. Bupropion hcl sr 100 (PA required), Budeprion XL Bupropion HCL (ER, SR; PA required for 100 For budeprion/bupropion SR (Wellbutrin SR 100 mg, 150 mg). ❖ Approvable for Bupropion hcl sr 100 (PA required), Budeprion XL Bupropion HCL (ER, SR; PA required for 100 For budeprion/bupropion SR (Wellbutrin SR 100 mg, 150 mg). ❖ Approvable for Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 (PA required), Budeprion XL Bupropion HCL (ER, SR; PA required for 100 and For budeprion/bupropion SR (Wellbutrin SR 100 mg, 150 mg). ❖ Approvable Bupropion hcl sr 100 bupropion hcl (75 mg tablet, 100 mg tablet) bupropion hcl sr (sr 100 bupropion xl (150 mg tablet, 300 mg tablet) mirtazapine (7.5 Bupropion hcl sr 100 Diluted hydrochloride acid, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium stearyl fumarate, titanium dioxide and is printed with edible black ink. In addition, the 100 mg tablet contains FD&C Red #40, the 150 mg tablet contains FD&C Blue #1 and D&C Yellow #10 Lake and the 200 mg tablet contains D&C Yellow #10 Lake. FDA approved dissolution test specifications differ from USP. 12. Bupropion - Clinical Pharmacology 12.1 Mechanism of Action The exact mechanism of the antidepressant action of bupropion is not known but is presumed to be related to noradrenergic and/or dopaminergic mechanisms. Bupropion is a relatively weak inhibitor of the neuronal reuptake of norepinephrine and dopamine and does not inhibit the reuptake of serotonin. Bupropion does not inhibit monoamine oxidase. 12.3 Pharmacokinetics Bupropion is a racemic mixture. The pharmacological activity and pharmacokinetics of the individual enantiomers have not been studied. The mean elimination half-life (±SD) of bupropion after chronic dosing is 21 (±9) hours, and steady-state plasma concentrations of bupropion are reached within 8 days. Absorption The absolute bioavailability of bupropion hydrochloride extended-release tablets (SR) in humans has not been determined because an intravenous formulation for human use is not available. However, it appears likely that only a small proportion of any orally administered dose reaches the systemic circulation intact. In rat and dog studies, the bioavailability of bupropion ranged from 5% to 20%. In humans, following oral administration of bupropion hydrochloride extended-release tablets (SR), peak plasma concentration (C max) of bupropion is usually achieved within 3 hours. In a trial comparing chronic dosing with bupropion hydrochloride extended-release tablets (SR) 150 mg twice daily to bupropion immediate-release formulation 100 mg 3 times daily, the steady state C maxfor bupropion after bupropion hydrochloride extended-release tablets (SR) administration was approximately 85% of those achieved after bupropion immediate-release formulation administration. Exposure (AUC) to bupropion was equivalent for both formulations. Bioequivalence was also demonstrated for all three major active metabolites (i.e., hydroxybupropion, threohydrobupropion and erythrohydrobupropion) for both C maxand AUC. Thus, at steady state, bupropion hydrochloride extended-release tablets (SR) given twice daily, and the immediate-release formulation of bupropion given Bupropion hcl sr 100 bupropion hcl (75 mg tablet, 100 mg tablet) bupropion hcl sr (sr 100 mg tablet, sr 150 mg tablet, sr 200 mg tablet) bupropion xl (150 mg Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 bupropion hcl er (sr) . 11 bupropion hcl er (xl) PAXLOVID (150/100) . 14. PAXLOVID (300/100) Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 (SR) may be resumed 24 hours after the last dose of linezolid or intravenous methylene blue. The risk of administering methylene blue by non-intravenous routes (such as oral tablets or by local injection) or in intravenous doses much lower than 1 mg/kg with bupropion hydrochloride extended-release tablets (SR) is unclear. The clinician should, nevertheless, be aware of the possibility of a drug interaction with such use [see Contraindications (4), Drug Interactions (7.6)] . 3. Dosage Forms and Strengths • 100 mg – Red colored, round biconvex bevel edged film coated tablets imprinted with 'V1 48' on one side and plain on other side. • 150 mg – Green colored, round biconvex bevel edged film coated tablets imprinted with 'V1 49' on one side and plain on other side. • 200 mg – Yellow colored, round biconvex bevel edged film coated tablets imprinted with 'V1 50' on one side and plain on other side. 4. Contraindications • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients with a seizure disorder. • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients with a current or prior diagnosis of bulimia or anorexia nervosa as a higher incidence of seizures was observed in such patients treated with the immediate-release formulation of bupropion [see Warnings and Precautions (5.3)]. • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients undergoing abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and antiepileptic drugs [see Warnings and Precautions (5.3), Drug Interactions (7.3)]. • The use of MAOIs (intended to treat psychiatric disorders) concomitantly with bupropion hydrochloride extended-release tablets (SR) or within 14 days of discontinuing treatment with bupropion hydrochloride extended-release tablets (SR) are contraindicated. There is an increased risk of hypertensive reactions when bupropion hydrochloride extended-release tablets (SR) are used concomitantly with MAOIs. The use of bupropion hydrochloride extended-release tablets (SR) within 14 days of discontinuing treatment with an MAOI is also contraindicated. Starting bupropion hydrochloride extended-release tablets (SR) in a patient treated with reversible MAOIs such as linezolid or intravenous methylene blue is contraindicated [see Dosage and Administration (2.4, 2.5), Warnings and Precautions (5.4), Drug Interactions (7.6)]. • Bupropion hydrochloride Wellbutrin SR: 100 mg, 150 mg, 200 mg. Generic: 100 15 years of clinical experience with bupropion HCl: from bupropion to bupropion SR to bupropion XL. Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 (PA required), Budeprion XL Bupropion HCL (ER, SR; PA required for 100 and For budeprion/bupropion SR (Wellbutrin SR 100 mg, 150 mg). ❖ Approvable Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 bupropion hcl tab 75 mg bupropion hcl tab 100 mg bupropion hcl tab er 12hr 100 mg (Wellbutrin sr) bupropion hcl tab er 12hr 150 mg (Wellbutrin Bupropion hcl sr 100 Also, if there is a shortage in the marketplace, we may fill your bupropion hcl er (sr) tb12 100 mg 47 bupropion hcl er (sr) tb12 Bupropion hcl sr 100 (SR) may be resumed 24 hours after the last dose of linezolid or intravenous methylene blue. The risk of administering methylene blue by non-intravenous routes (such as oral tablets or by local injection) or in intravenous doses much lower than 1 mg/kg with bupropion hydrochloride extended-release tablets (SR) is unclear. The clinician should, nevertheless, be aware of the possibility of a drug interaction with such use [see Contraindications (4), Drug Interactions (7.6)] . 3. Dosage Forms and Strengths • 100 mg – Red colored, round biconvex bevel edged film coated tablets imprinted with 'V1 48' on one side and plain on other side. • 150 mg – Green colored, round biconvex bevel edged film coated tablets imprinted with 'V1 49' on one side and plain on other side. • 200 mg – Yellow colored, round biconvex bevel edged film coated tablets imprinted with 'V1 50' on one side and plain on other side. 4. Contraindications • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients with a seizure disorder. • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients with a current or prior diagnosis of bulimia or anorexia nervosa as a higher incidence of seizures was observed in such patients treated with the immediate-release formulation of bupropion [see Warnings and Precautions (5.3)]. • Bupropion hydrochloride extended-release tablets (SR) are contraindicated in patients undergoing abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and antiepileptic drugs [see Warnings and Precautions (5.3), Drug Interactions (7.3)]. • The use of MAOIs (intended to treat psychiatric disorders) concomitantly with bupropion hydrochloride extended-release tablets (SR) or within 14 days of discontinuing treatment with bupropion hydrochloride extended-release tablets (SR) are contraindicated. There is an increased risk of hypertensive reactions when bupropion hydrochloride extended-release tablets (SR) are used concomitantly with MAOIs. The use of bupropion hydrochloride extended-release tablets (SR) within 14 days of discontinuing treatment with an MAOI is also contraindicated. Starting bupropion hydrochloride extended-release tablets (SR) in a patient treated with reversible MAOIs such as linezolid or intravenous methylene blue is contraindicated [see Dosage and Administration (2.4, 2.5), Warnings and Precautions (5.4), Drug Interactions (7.6)]. • Bupropion hydrochloride Bupropion hcl sr 100 The Benefits of Bupropion HCL SR 100 mg for Weight Loss . Bupropion HCL SR 100 mg is a medication that has been used for various purposes, including the Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 Also, if there is a shortage in the marketplace, we may fill your bupropion hcl er (sr) tb12 100 mg 62 bupropion hcl er (sr) tb12 Bupropion hcl sr 100 Wellbutrin SR comes in 100 mg, 150 mg, and 200 mg tablets. It is Bupropion HCl: From Bupropion to Bupropion SR to Bupropion XL. Bupropion hcl sr 100 Aplenzin ; Forfivo xl ; Wellbutrin sr ; Wellbutrin xl. Bupropion HCl Tab ER ; bupropion hbr tab er ; bupropion hcl tab ; bupropion hcl tab er. 100 ; 100 MG ; Bupropion hcl sr 100 Paradigms. In primate models assessing the positive-reinforcing effects of psychoactive drugs, bupropion was self-administered intravenously. In rats, bupropion produced amphetamine-like and cocaine-like discriminative stimulus effects in drug discrimination paradigms used to characterize the subjective effects of psychoactive drugs. 10. Overdosage 10.1 Human Overdose Experience Overdoses of up to 30 grams or more of bupropion have been reported. Seizure was reported in approximately one-third of all cases. Other serious reactions reported with overdoses of bupropion alone included hallucinations, loss of consciousness, mental status changes, sinus tachycardia, ECG changes such as conduction disturbances (including QRS prolongation) or arrhythmias, clonus, myoclonus, and hyperreflexia. Fever, muscle rigidity, rhabdomyolysis, hypotension, stupor, coma, and respiratory failure have been reported mainly when bupropion was part of multiple drug overdoses. Although most patients recovered without sequelae, deaths associated with overdoses of bupropion alone have been reported in patients ingesting large doses of the drug. Multiple uncontrolled seizures, bradycardia, cardiac failure, and cardiac arrest prior to death were reported in these patients. 10.2 Overdosage Management Consult a Certified Poison Control Center for up-to-date guidance and advice. Call 1-800-222-1222 or refer to www.poison.org. There are no known antidotes for bupropion. In case of an overdose, provide supportive care, including close medical supervision and monitoring. Consider the possibility of multiple drug overdose. Ensure an adequate airway, oxygenation, and ventilation. Monitor cardiac rhythm and vital signs. Induction of emesis is not recommended. 11. Bupropion Description Bupropion hydrochloride, USP is an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines. It is designated as (±)-1-(3-chlorophenyl)-2-[1,1-dimethylethyl)amino]-1-propanone hydrochloride. The molecular weight is 276.20. The molecular formula is C 13H 18ClNO•HCl. Bupropion hydrochloride is white powder, and soluble in water, 0.1 N Hydrochloric acid and in alcohol. The structural formula is: Bupropion hydrochloride extended-release tablets USP (SR) are supplied for oral administration as 100 mg (red), 150 mg (green), and 200 mg (yellow), film-coated, sustained-release tablets. Each tablet contains the labeled amount of bupropion hydrochloride USP and the inactive ingredients: colloidal silicon dioxide, bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 bupropion HCl, BUPROPION XL, TAB ER 24H ; bupropion HCl, WELLBUTRIN XL, TAB ER 24H ; bupropion HCl, BUPROPION HCL SR, TAB SR 12H ; bupropion HCl, WELLBUTRIN SR Bupropion hcl sr 100 Aplenzin ; Forfivo xl ; Wellbutrin sr ; Wellbutrin xl. Bupropion HCl Tab ER ; bupropion hbr tab er ; bupropion hcl tab ; bupropion hcl tab er. 100 ; 100 MG ; Bupropion hcl sr 100 BUPROPION HCL SR 100 MG TABLET. Drug Details. General. Brand Name: BUPROPION HCL SR 100 MG TABLET. Generic Name: bupropion HCl. Manufacturer: SLATE RUN PHARM. Bupropion hcl sr 100 Wellbutrin SR (bupropion. HCl), generic. SR tablets. 100, 150, 200 mg Available generically. Wellbutrin XL (bupropion. HCl), generic. ER Bupropion hcl sr 100
Bupropion HCl SR 100 mg Tablets (Generic Wellbutrin SR)
BUPROPION HCL SR 100 MG TABLET