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J Pharm Pharmacol. 1992;44:1023–6.Article CAS PubMed Google Scholar Wu J, Shao Y, Liu J, Chen G, Ho PC. The medicinal use of realgar (As4S4) and its recent development as an anticancer agent. J Ethnopharmacol. 2011;135:595–602.Article CAS PubMed Google Scholar Li Y, Shi S, Wu S, Guo F, Xiong Y. Study on materiomic release kinetics of toxic Xiaohuoluo pills. China J Tradit Chinese Med Pharm. 2014;29:3614–8.CAS Google Scholar Guo Z, Ling D, Zhang J, Ge W, Shi S. Materiomic release kinetics of Longdan Xiegan pill. Chinese Tradit Herb Drugs. 2010;41:1806–8. Google Scholar Wang L. Thinking over clinical application of large-prescription pill of TCM. Shan Dong Zhong Yi Yao Za Zhi. 2004;23:131–3. Google Scholar Wang GH, Lan R, De Zhen X, Zhang W, Xiang J, Cai DF. An-Gong-Niu-Huang Wan protects against cerebral ischemia induced apoptosis in rats: up-regulation of Bcl-2 and down-regulation of Bax and caspase-3. J Ethnopharmacol. 2014;154:156–62.Article PubMed Google Scholar Chinese Pharmacopeia Commission. Angong Niuhuang Pills. Pharmacopoeia People’s Repub China. Beijing; 2015. p. 538.Lu YF, Yan JW, Wu Q, Shi JZ, Liu J, Shi JS. Realgar- and cinnabar-containing an-Gong-Niu-Huang Wan (AGNH) is much less acutely toxic than sodium arsenite and mercuric chloride. Chem Biol Interact. 2011;189:134–40.Article CAS PubMed Google Scholar Pan H, Wang P, Wang N. Clinical application of Angong Niuhuang pill and its similar formula. J New Chinese Med. 2001;33:64–6. Google Scholar Luo J, Xu H, Chen K. Systematic review of compound danshen dropping pill: a chinese patent medicine for acute myocardial infarction. Evidence-based Complement Altern Med. 2013;2013:1–15. Google Scholar Ren L, Wang J, Feng L, Wang S, Li J. Efficacy of Suxiao Jiuxin pill on coronary BLUE SHIELD OF CALIFORNIA (2024): Blue Shield of California, Google pill' Google pill oval shaped dark blue pills with F82 written on them. 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